The objective of this continuation proposal is to train outstanding young M.D.s, M.D./Ph.D.s, and Ph.D.s and talented predoctoral Ph.D. and M.D./Ph.D. students for a successful career in investigative nephrology. Mount Sinai School of Medicine offers diverse scientific opportunities in an outstanding research environment with faculty dedicated to training physician-scientists and predoctoral students for a career in academic nephrology.

All candidates for this training program will be expected to devote a minimum of two years to training in either basic or clinical research. The trainees will select a preceptor from one of the eight areas encompassed by this program: virology and gene therapy, immunology/transplant, genetics, developmental and stem cell biology, adhesion molecules and matrix, molecular basis of transport, vascular biology, and clinical research. Throughout the training period, trainees will devote approximately 90 percent of their time to research. The primary focus and vast majority of the trainee's time will be devoted to working on a specific, individualized research project under the guidance of one or more faculty preceptors. In addition, trainees will participate in weekly laboratory meetings, spend a portion of their time attending specific divisional, departmental and institutional research-oriented conferences, and will enroll in at least one didactic, graduate-level course during the first- and second-years of training. M.D.s will not be assigned clinical duties during the period of their training.